What Can Cause Swollen Occipital Lymph Nodes?

Medically Reviewed By Meredith Goodwin, MD, FAAFP

Your occipital lymph nodes are located in the back of your head, by the base of your skull. Swollen occipital lymph nodes may indicate an infection or underlying condition, such as psoriasis, an autoimmune disorder, or sometimes cancer. Your lymphatic system is an essential part of your immune system. It helps your body resist infections by moving white blood vessels throughout your body.

Lymph nodes are oval-shaped glands that make white blood cells. Your head and neck have over 300 Trusted Source PubMed Central Highly respected database from the National Institutes of Health Go to source lymph nodes. Your occipital glands are at the base of your head.

This article explains what might cause your occipital glands to swell, along with treatments and when you should see a doctor.

Bacterial infections

Someone feels the lymph nodes behind their ear.
Maskot/Getty Images

An infection near your head or neck can cause swelling Trusted Source PubMed Central Highly respected database from the National Institutes of Health Go to source in your occipital lymph nodes. If the infection is widespread, lymph nodes in different areas of your body may also swell.

Your lymph nodes bulge as your body rushes to make white blood cells.

Some bacterial infections can cause occipital lymph nodes to swell, including:

Apart from swollen lymph nodes, symptoms that can appear with a bacterial infection include:

Drinking plenty of water to stay hydrated may help manage your symptoms. If necessary, a doctor may prescribe antibiotics

Viral infections

Many viral infections can also cause swollen lymph nodes.

Mononucleosis

Mononucleosis (mono) is a widespread viral infection that can cause lymph node swelling, including swelling in your occipital lymph nodes.

If you have mono, you may experience:

Treatment for mono mainly involves Trusted Source PubMed Central Highly respected database from the National Institutes of Health Go to source relieving your symptoms while you recover. Symptom relief can include pain or fever-reducing medications, hydration, and rest.

Rubella

Rubella is a contagious viral infection. High vaccination rates in the United States make rubella rare Trusted Source Centers for Disease Control and Prevention (CDC) Governmental authority Go to source

If you do develop rubella, your occipital lymph nodes can swell as they create white blood cells to help fight the infection. Research Trusted Source PubMed Central Highly respected database from the National Institutes of Health Go to source suggests that your lymph nodes can swell up to 5 to 10 days before a rash develops.

Other symptoms of rubella include:

There is no specific Trusted Source Centers for Disease Control and Prevention (CDC) Governmental authority Go to source treatment for rubella. Drinking enough water, rest, and pain relief may help soothe your symptoms.

Ringworm

Tinea capitis — ringworm — is a fungal skin infection that causes a discolored, circular rash. If ringworm is on your scalp, it may cause Trusted Source PubMed Central Highly respected database from the National Institutes of Health Go to source swollen occipital lymph nodes.

A medical professional may recommend an oral antifungal medication to help clear ringworm. Creams and lotions are not effective on scalps. You may need to use medication every day for several months Trusted Source Centers for Disease Control and Prevention (CDC) Governmental authority Go to source to resolve a fungal infection.

Once the infection clears, swelling in your occipital lymph nodes should shrink.

Head lice

Head lice are small parasites that show up around the base of your hair. The Centers for Disease Control and Prevention (CDC) reports that children are more likely Trusted Source Centers for Disease Control and Prevention (CDC) Governmental authority Go to source to get head lice. 

In some cases, head lice may cause swollen occipital lymph nodes.

Head lice can cause:

You can treat head lice by:

  • removing the lice and eggs with a lice comb
  • applying medicated creams
  • washing your brushes, bedsheets, and clothes

Once the infection resolves, your occipital lymph nodes should return to their pre-infection size. 

Psoriasis

Psoriasis is a chronic skin condition that causes dry patches that burn or itch. With psoriasis, your immune system tells your skin cells to grow faster, so they build up.

Psoriasis can cause Trusted Source PubMed Central Highly respected database from the National Institutes of Health Go to source swollen lymph nodes in some people. 

A doctor may recommend the following medical interventions for psoriasis:

  • light therapy 
  • retinoid creams
  • medications such as methotrexate or cyclosporine

Melanoma

Melanoma is a type of skin cancer. If melanoma is on your neck or head, your occipital nodes may swell Trusted Source PubMed Central Highly respected database from the National Institutes of Health Go to source as they filter the cancer cells.

Melanoma is the most aggressive type of skin cancer, meaning it worsens very quickly. 

Sometimes melanoma starts as a mole. Regularly check your skin for moles that:

  • are asymmetrical
  • have a range of colors or an irregular border
  • larger than a pencil eraser
  • changing quickly in color, shape, or size


Your medical team may use a combination of these treatments to address melanoma:

  • skin surgery
  • radiation
  • immune checkpoint inhibitors

Your lymph nodes are a connected system that runs throughout your body, so cancer can spread to different areas. Seek prompt medical treatment if you see any suspicious moles or have a family history of skin cancers.

Lymphoma

Lymphoma is a medical term used to describe any cancer that starts in your lymphatic system. Your lymphatic system includes any structure that supplies or transports white blood cells, such as your lymph nodes.

Symptoms of lymphoma may include:

  • swollen lymph nodes
  • fever
  • sweating at night
  • fatigue
  • losing weight for no known reason

Your medical team may treat lymphoma with the following approaches:

Autoimmune conditions

Autoimmune conditions occur when your immune system becomes overactive and damages healthy body structures. These conditions cause widespread inflammation, which can cause Trusted Source PubMed Central Highly respected database from the National Institutes of Health Go to source lymph node swelling throughout your body. 

Some autoimmune conditions that can affect the occipital lymph nodes include:

Treatment options vary greatly depending on what autoimmune condition you have. Your medical team may recommend a combination of medications and lifestyle approaches to address your personal condition.

When to see a doctor

Contact a doctor promptly if you have any of the following symptoms:

  • swelling in your lymph nodes that lasts longer than 2 weeks
  • fever, night sweats, or chills
  • swollen lymph nodes with no other signs of illness
  • lymph nodes that feel hardened
  • any other symptoms that are frequent, persistent, or seem severe

A doctor can evaluate your swollen occipital lymph nodes and develop a personalized treatment plan for you.

Summary

Your occipital lymph nodes are at the base of your skull. Usually, you don’t notice these glands. However, when they swell, you may be able to see or feel an oval lump of tissue.

Infections can cause swollen occipital lymph nodes, including infections from bacteria, viruses, fungi, and parasites like head lice. Other conditions, like autoimmune disorders and cancer, can also lead to swollen lymph nodes.

Talk with a doctor promptly about any persistent swelling in your lymph nodes, or swelling alongside any other frequent, long-lasting, or severe symptoms.

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Medical Reviewer: Meredith Goodwin, MD, FAAFP
Last Review Date: 2025 Mar 31
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